Benzodiazepine boxed warnings

  • PTCB PTCE
  • Medications
  • Select all that apply
  • Difficulty 3 of 5

Question

Which concerns belong in a pharmacy technician's reference on benzodiazepine boxed warnings? Select all that apply.

  1. Serious sedation when combined with an opioid✓ Correct

    The warning identifies profound sedation as a possible consequence of that combination.

  2. Breathing suppression when combined with an opioid✓ Correct

    The combination can cause respiratory depression.

  3. Life-threatening withdrawal after abrupt discontinuation✓ Correct

    Abrupt cessation can trigger dangerous withdrawal reactions.

  4. An assurance that dependence cannot develop✗ Incorrect

    Continued use may produce physical dependence.

  5. An assurance that opioid combinations prevent coma✗ Incorrect

    Coma is among the possible outcomes named in the warning.

Answer

A. Serious sedation when combined with an opioid · B. Breathing suppression when combined with an opioid · C. Life-threatening withdrawal after abrupt discontinuation

Rationale

Opioids used alongside benzodiazepines can cause severe central nervous system and breathing effects. Dependence and dangerous withdrawal are also warning concerns.

RememberBenzodiazepines carry warnings about opioid combinations and withdrawal.

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