Nebulizer solution dilution
Question
For an adult inhalation preparation, a pharmacist requests 8 mL of 10% acetylcysteine using 20% stock and a labeled diluent. How many mL of stock should the pharmacy technician measure?
Answer
B. 4 mL
Rationale
The inhalation label permits the stronger solution to be diluted. The requested volume is the entire mixture, not the amount of stock alone.
Worked solution: C1 × V1 = C2 × V2 → V1 = 10 × 8 ÷ 20 = 4 mL of stock.
RememberUse the final mixture volume when calculating stock needed for a dilution.
Sources
- Acetylcysteine (acetylcysteine) oral, respiratory (inhalation) prescribing information, Hospira, Inc.
- Acetylcysteine (acetylcysteine) intravenous prescribing information, Glenmark Pharmaceuticals Inc., USA
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